Description

3-Iodo-7-Azaindole-5-Carboxylic Acid is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a reactive iodine substituent with a carboxylic acid functional group on a 7-azaindole scaffold, enabling precise derivatization for complex molecule construction. This compound is essential for medicinal chemistry researchers and fine chemical manufacturers developing novel pharmaceuticals, particularly kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile reactive sites.
• Chemical Biology Probe Development: Serves as a building block for creating molecular probes to study enzyme function and cellular signaling processes.
• Agrochemical Synthesis: Potential intermediate in the development of new, high-performance active ingredients for crop protection.
• Material Science: Can be utilized in the creation of specialized organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	3-Iodo-7-Azaindole-5-Carboxylic Acid
CAS No.	1060816-80-9
Molecular Formula	C8H5IN2O2
Molecular Weight	288.04 g/mol
Synonyms	3-Iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 5-Carboxy-3-iodo-7-azaindole; 3-Iodo-7-azaindole-5-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-5-carboxylic acid, 3-iodo-; 3-Iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 3-Iodo-7-aza-indole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-7-Azaindole-5-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by NMR and MS), and impurity profiles is supplied with each shipment. Specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.