Description

2-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles for cross-coupling reactions.
• Chemical Biology: Serves as a scaffold for developing chemical probes to study enzyme function and cellular signaling pathways.
• Agrochemical Research: Employed in the discovery of new active ingredients for crop protection.
• Material Science: Potential building block for organic electronic materials and advanced polymers.

Basic Information

Product Name	2-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1060815-90-8
Molecular Formula	C6H3ClIN3
Molecular Weight	279.46 g/mol
Synonyms	7H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-5-iodo-; 2-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-5-iodopyrrolo[2,3-d]pyrimidine; 5-Iodo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (CAS 1060815-90-8)
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.