Description

4-Trifluoromethyl-5-Azaindole-2-Carboxylic Acid Ethyl Ester is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in the trifluoromethyl group and azaindole scaffold, which are critical for modulating the potency, metabolic stability, and bioavailability of lead compounds. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, leveraging the biological activity of the azaindole core.
• Material Science: Serves as a precursor for specialty chemicals and functional materials requiring fluorinated heterocycles.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry and biochemical studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Item	Details
Product Name	4-Trifluoromethyl-5-Azaindole-2-Carboxylic Acid Ethyl Ester
CAS No.	1060815-19-1
Molecular Formula	C11H9F3N2O2
Molecular Weight	258.20 g/mol
Synonyms	Ethyl 4-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 4-(trifluoromethyl)-, ethyl ester; 4-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid ethyl ester; 5-Azaindole-2-carboxylic acid, 4-trifluoromethyl-, ethyl ester; 4-Trifluoromethyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethyl-5-Azaindole-2-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.