Description

1,3-Bis(2,6-Diisopropylphenyl)-1H-Imidazol-2(3H)-One is a high-value, sterically hindered imidazolone derivative, primarily recognized as a key precursor to N-Heterocyclic Carbene (NHC) ligands. This compound matters because it enables the synthesis of highly active and selective catalysts, which are critical for advancing research and production in sophisticated organic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical, fine chemical, and advanced materials sectors who require reliable, high-purity building blocks for catalyst development.

Application

• N-Heterocyclic Carbene (NHC) Ligand Synthesis: Serves as the direct precursor for generating a wide array of sterically demanding NHC ligands used in organometallic catalysis.
• Homogeneous Catalysis: The resulting NHC-metal complexes (e.g., with Pd, Ru, Au) are employed in cross-coupling reactions (Heck, Suzuki-Miyaura), olefin metathesis, and hydrogenation processes.
• Pharmaceutical Intermediate Manufacturing: Facilitates the development of novel synthetic routes for complex drug molecules and active pharmaceutical ingredients (APIs) requiring specialized catalytic steps.
• Polymerization Catalysts: Used in the creation of catalysts for the controlled polymerization of olefins and other monomers to produce advanced polymeric materials.
• Academic & Industrial R&D: A fundamental reagent for exploring new catalytic methodologies and reaction mechanisms in both university and corporate research laboratories.
• Fine Chemical Synthesis: Enables the efficient and selective synthesis of high-value specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	1,3-Bis(2,6-Diisopropylphenyl)-1H-Imidazol-2(3H)-One
CAS No.	1060651-05-9
Molecular Formula	C27H36N2O
Molecular Weight	404.59 g/mol
Synonyms	1,3-Bis(2,6-diisopropylphenyl)imidazolidin-2-one; 1,3-Di(2,6-diisopropylphenyl)imidazolidin-2-one; N,N'-Bis(2,6-diisopropylphenyl)imidazolidin-2-one; Imidazolidin-2-one, 1,3-bis(2,6-diisopropylphenyl)-; NHC Precursor; SIPr·HCl precursor (common starting material); 1,3-Bis(2,6-diisopropylphenyl)-2-imidazolidinone
EINECS	Contact for details

Quality Control

Our 1,3-Bis(2,6-Diisopropylphenyl)-1H-Imidazol-2(3H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive catalytic applications. We provide comprehensive analytical data including HPLC purity, NMR (1H and 13C) for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are available upon request and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.