Description

1H-Pyrido[4,3-B]Indole, 6-Bromo-2,3,4,5-Tetrahydro-, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate with a distinct brominated tetracyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique fused ring system.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Item	Details
Product Name	1H-Pyrido[4,3-B]Indole, 6-Bromo-2,3,4,5-Tetrahydro-, Hydrochloride (1:1)
CAS No.	1059630-11-3
Molecular Formula	C12H12BrClN2
Molecular Weight	299.59 g/mol
Synonyms	6-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride; 6-Bromo-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride; 6-Bromo-THPI hydrochloride; 6-Bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole HCl; 1059630-11-3; 6-Bromo-1,2,3,4-tetrahydro-9H-β-carboline hydrochloride; 6-Bromo-tetrahydro-β-carboline hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrido[4,3-B]Indole, 6-Bromo-2,3,4,5-Tetrahydro-, Hydrochloride (1:1) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement in-process controls and final release testing, including advanced chromatographic methods, to meet the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.