Description

Boronic Acid, B -[2,5-Dimethyl-4-(Trimethylsilyl)Phenyl] is a specialized organoboron compound featuring a sterically hindered aromatic ring system. This compound is a valuable synthetic intermediate, prized for its role in facilitating key carbon-carbon bond-forming reactions, particularly in the synthesis of complex pharmaceutical and agrochemical targets. It is essential for R&D chemists and process development scientists working in advanced organic synthesis, medicinal chemistry, and materials science.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for constructing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and insecticides with enhanced efficacy.
• Materials Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity reagents for studying protein function.
• Process Chemistry & Scale-up: Employed in the development of robust, scalable synthetic routes for commercial manufacturing.

Basic Information

Product Name	Boronic Acid, B -[2,5-Dimethyl-4-(Trimethylsilyl)Phenyl]
CAS No.	1059575-28-8
Molecular Formula	C11H19BO2Si
Molecular Weight	222.17 g/mol
Synonyms	[2,5-Dimethyl-4-(trimethylsilyl)phenyl]boronic acid; (2,5-Dimethyl-4-trimethylsilylphenyl)boronic acid; 4-Trimethylsilyl-2,5-dimethylbenzeneboronic acid; B-(2,5-Dimethyl-4-(trimethylsilyl)phenyl)boronic acid; 2,5-Dimethyl-4-(trimethylsilyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B -[2,5-Dimethyl-4-(Trimethylsilyl)Phenyl] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.