Description

2-Morpholino-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is a high-purity, advanced pharmaceutical intermediate and building block of significant value in modern synthetic chemistry. Its core value lies in the unique combination of a morpholine ring and a pinacol boronate ester group, enabling precise cross-coupling reactions for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing new active ingredients via Suzuki-Miyaura coupling methodologies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester moiety serves as a crucial coupling partner for forming carbon-carbon bonds with aryl halides, enabling the construction of complex biaryl structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the morpholine and boronate functionalities contribute to biological activity and molecular diversity.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of activity-based probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules and scaled-up processes.

Basic Information

Product Name	2-Morpholino-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide
CAS No.	1059171-55-9
Molecular Formula	C18H27BN2O4
Molecular Weight	346.23 g/mol
Synonyms	N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-morpholinoacetamide; 2-Morpholino-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 3-(2-Morpholinoacetamido)phenylboronic acid pinacol ester; (3-(2-Morpholinoacetamido)phenyl)boronic acid pinacol ester; CAS 1059171-55-9
EINECS	Contact for details

Quality Control

Every batch of 2-Morpholino-n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is produced and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.