Description

Thiophene, 5-Ethynyl-2,3-Dimethyl- is a high-value, multi-functional heterocyclic building block featuring a reactive ethynyl group on a dimethyl-substituted thiophene core. This compound matters for its unique reactivity profile, enabling advanced synthesis in materials science and pharmaceutical research through cross-coupling and cycloaddition reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics sectors for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Organic Semiconductor Precursor: Serves as a critical building block for π-conjugated systems in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organometallic complexes.
• Polymer and Material Science: Used to create functionalized polymers and advanced materials with tailored electronic or optical properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies, including click chemistry and Sonogashira couplings.

Basic Information

Product Name	Thiophene, 5-Ethynyl-2,3-Dimethyl-
CAS No.	1057670-09-3
Molecular Formula	C8H8S
Molecular Weight	136.22 g/mol
Synonyms	5-Ethynyl-2,3-dimethylthiophene; 2,3-Dimethyl-5-ethynylthiophene; 5-Ethynyl-2,3-dimethylthiophene; 2,3-Dimethylthiophene-5-ethyne; 5-Ethynyl-2,3-dimethyl-1-thiophene; 2,3-Dimethyl-5-ethynyl-1-thiophene; 5-Ethynyl-2,3-dimethylthiofuran (archaic); 1057670-09-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Thiophene, 5-Ethynyl-2,3-Dimethyl- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR, HPLC, and GC-MS analysis. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.