Description

Benzene, 4-Bromo-2-Ethynyl-1-Methoxy- is a specialized aromatic building block featuring a bromo substituent, an ethynyl group, and a methoxy group on the benzene ring, making it a versatile intermediate for advanced organic synthesis. This compound is valued for its ability to participate in cross-coupling reactions and serve as a precursor for complex molecular architectures in research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for molecules requiring a functionalized aromatic core.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where its specific substitution pattern can influence biological activity.
• Material Science Research: Acts as a monomer or building block for the synthesis of advanced polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: The bromo and ethynyl groups make it an excellent substrate for Sonogashira, Suzuki, and other palladium-catalyzed coupling reactions to create complex biaryl or conjugated systems.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags due to the reactivity of the alkyne group for "click chemistry" applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Detail
Product Name	Benzene, 4-Bromo-2-Ethynyl-1-Methoxy-
CAS No.	1057669-94-9
Molecular Formula	C9H7BrO
Molecular Weight	211.06 g/mol
Synonyms	4-Bromo-2-ethynyl-1-methoxybenzene; 1-Bromo-4-ethynyl-3-methoxybenzene; 2-Ethynyl-4-bromoanisole; 4-Bromo-2-ethynylanisole; 3-Methoxy-6-bromophenylacetylene
EINECS	Contact for details

Quality Control

Our Benzene, 4-Bromo-2-Ethynyl-1-Methoxy- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.