Description

1-[2-(Trifluoromethyl)Pyridin-3-Yl]Methanamine is a high-value trifluoromethylated pyridine derivative, a versatile building block prized for its ability to impart metabolic stability and enhanced lipophilicity to target molecules. Its primary commercial value lies in accelerating research and development within the pharmaceutical and agrochemical sectors. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the synthesis of small molecule drugs and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for central nervous system (CNS) targets, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a building block for functional materials.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Fluorinated Liquid Crystal Research: Acts as a starting material for novel fluorinated components in display technology.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring this specific fluorinated amine motif.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Pyridin-3-Yl]Methanamine
CAS No.	1056162-06-1
Molecular Formula	C7H7F3N2
Molecular Weight	176.14 g/mol
Synonyms	[2-(Trifluoromethyl)pyridin-3-yl]methanamine; 3-(Aminomethyl)-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-3-pyridinemethanamine; 1-(2-Trifluoromethylpyridin-3-yl)methanamine; (2-(Trifluoromethyl)pyridin-3-yl)methylamine; 3-Aminomethyl-2-trifluoromethylpyridine; 1056162-06-1; Contact for EINECS details.

Quality Control

Our 1-[2-(Trifluoromethyl)Pyridin-3-Yl]Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements for pharmaceutical R&D and cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.