Description

5-Mercaptopentanenitrile is a versatile sulfur-containing nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, featuring both a reactive thiol group and a nitrile moiety, which makes it indispensable for constructing complex molecular architectures. This intermediate is particularly needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications such as drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing thioether or modified cysteine motifs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that require specific sulfur-based functional groups.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Polymer Modification: Employed to introduce thiol functional groups into polymer backbones or surfaces for cross-linking or adhesion promotion.
• Bioconjugation Chemistry: Useful in the development of linkers for antibody-drug conjugates (ADCs) or protein labeling due to its reactive thiol.
• Material Science Research: Applied in the synthesis of novel organic frameworks and functional materials with tailored properties.

Basic Information

Item	Details
Product Name	5-Mercaptopentanenitrile
CAS No.	1053658-37-9
Molecular Formula	C5H9NS
Molecular Weight	115.20 g/mol
Synonyms	5-Mercaptovaleronitrile; Pentanenitrile, 5-mercapto-; 5-Sulfanylpentanenitrile; 5-Cyanopentanethiol; 5-Thiocyanatopentanenitrile (related); Valeronitrile, 5-mercapto-
EINECS	Contact for details

Quality Control

Our 5-Mercaptopentanenitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its property of being easily oxidized, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Recommended storage temperature is 2-8°C for long-term preservation. Keep the container tightly sealed in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 90.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.