Description

2-Benzyl-1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific tetrahydroisoquinoline scaffold. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex bioactive molecules, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those with tetrahydroisoquinoline-based structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new active pharmaceutical ingredients (APIs).
• Preclinical Development: Serves as a critical raw material for producing compounds for pharmacological and toxicological evaluation.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis: Utilized in academic and industrial research for constructing complex heterocyclic compounds and exploring new synthetic methodologies.

Basic Information

Product Name	2-Benzyl-1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid
CAS No.	1053656-29-3
Molecular Formula	C17H17NO2
Molecular Weight	267.32 g/mol
Synonyms	8-Carboxy-2-benzyl-1,2,3,4-tetrahydroisoquinoline; 2-Benzyl-1,2,3,4-tetrahydro-8-isoquinolinecarboxylic acid; 1,2,3,4-Tetrahydro-2-(phenylmethyl)-8-isoquinolinecarboxylic acid; BTHIQ-8-COOH; 2-Benzyl-THIQ-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Benzyl-1,2,3,4-Tetrahydroisoquinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.