Description

1-(Isoquinolin-5-Yl)Propan-1-One is a high-purity organic building block and key synthetic intermediate of significant interest in advanced chemical research and development. Its unique isoquinoline-based ketone structure makes it a versatile precursor for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Serves as a key precursor in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and synthesis of advanced organic materials, including ligands for catalysis and organic semiconductors.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex polycyclic and heterocyclic frameworks.
• Academic & Industrial R&D: Essential for methodological studies, library synthesis, and exploring new chemical spaces in both university and corporate research laboratories.

Basic Information

Product Name	1-(Isoquinolin-5-Yl)Propan-1-One
CAS No.	1053656-01-1
Molecular Formula	C₁₂H₁₁NO
Molecular Weight	185.22 g/mol
Synonyms	1-Propanone, 1-(5-isoquinolinyl)-; 5-Propanoylisoquinoline; 1-(5-Isoquinolyl)-1-propanone; 1-(Isoquinolin-5-yl)propan-1-one; 5-Acetylisoquinoline (common name); Isoquinolin-5-yl ethyl ketone; 5-Propanoylisoquinoline; 1-(5-Isoquinolinyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 1-(Isoquinolin-5-Yl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.