Description

(5,6-Dimethyl-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid, Hcl is a high-purity, functionalized thienopyrimidine derivative, a key scaffold in modern medicinal chemistry. This compound matters as a versatile and critical building block for pharmaceutical research and development, enabling the synthesis of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for structure-activity relationship (SAR) studies.
• Chemical Biology Probe Development: Acts as a precursor for developing tool compounds to study specific biological pathways and target validation.
• Agrochemical Research: Employed in the discovery of new active ingredients for crop protection, leveraging its heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	(5,6-Dimethyl-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid, Hcl
CAS No.	1052405-52-3
Molecular Formula	C12H14N4O2S • HCl
Molecular Weight	314.79 g/mol (Free base: 278.33 g/mol)
Synonyms	4-[(Carboxymethyl)amino]-5,6-dimethylthieno[2,3-d]pyrimidine hydrochloride; (5,6-Dimethylthieno[2,3-d]pyrimidin-4-ylamino)acetic acid hydrochloride; 2-[(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino]acetic acid hydrochloride; 4-Amino-5,6-dimethylthieno[2,3-d]pyrimidine-N-acetic acid HCl; Thieno[2,3-d]pyrimidine-4-acetic acid derivative, HCl salt; CAS 1052405-52-3
EINECS	Contact for details

Quality Control

Our (5,6-Dimethyl-Thieno[2,3-D]Pyrimidin-4-Ylamino)-Acetic Acid, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.