Description

1-(2,3-Dihydro-1H-Indol-1-Yl)-2-(Methylamino)-1-Ethanone Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical building block for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex heterocyclic compounds, including indole and indoline derivatives.
• Active Pharmaceutical Ingredient (API) Development: Serves as a building block in the synthesis of potential APIs requiring specific indole-based pharmacophores.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for studies in organic synthesis methodology and bioorganic chemistry.

Basic Information

Product Name	1-(2,3-Dihydro-1H-Indol-1-Yl)-2-(Methylamino)-1-Ethanone Hydrochloride
CAS No.	1049769-37-0
Molecular Formula	C11H15ClN2O
Molecular Weight	226.70 g/mol
Synonyms	N-Methyl-2-(2,3-dihydro-1H-indol-1-yl)-2-oxoethanamine hydrochloride; 1-(2,3-Dihydro-1H-indol-1-yl)-2-(methylamino)ethanone HCl; 2-(Methylamino)-1-(2,3-dihydro-1H-indol-1-yl)ethanone hydrochloride; 2-(Methylamino)-1-(indolin-1-yl)ethanone hydrochloride; N-Methyl-1-indolin-1-yl-2-oxoethanamine hydrochloride; 1049769-37-0; 1H-Indole-1-ethanone, 2,3-dihydro-2-(methylamino)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dihydro-1H-Indol-1-Yl)-2-(Methylamino)-1-Ethanone Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.