Description

4-(1,3-Dioxo-1,5,10,10A-Tetrahydro-Imidazo[1,5-B]Isoquinolin-2-Yl)-Butyric Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and neurology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for complex small-molecule therapeutics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for producing target active pharmaceutical ingredients.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	4-(1,3-Dioxo-1,5,10,10A-Tetrahydro-Imidazo[1,5-B]Isoquinolin-2-Yl)-Butyric Acid
CAS No.	1049710-99-7
Molecular Formula	C₁₅H₁₄N₂O₄
Molecular Weight	286.28 g/mol
Synonyms	4-(1,3-Dioxo-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-2(3H)-yl)butanoic acid; 2-(3-Carboxypropyl)-1,3-dioxo-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinoline; Butanoic acid, 4-(1,3-dioxo-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-2(3H)-yl)-; CAS 1049710-99-7; Imidazoisoquinoline butyric acid derivative.
EINECS	Contact for details

Quality Control

Our 4-(1,3-Dioxo-1,5,10,10A-Tetrahydro-Imidazo[1,5-B]Isoquinolin-2-Yl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.