Description

tert-Butyl 4-(1H-Indol-5-Yl)Piperidine-1-Carboxylate is a high-purity, protected piperidine-indole hybrid compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, nitrogen-rich scaffold for constructing complex molecules with potential biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperidine and indole moieties.
• Agrochemical Development: Serves as a precursor in the creation of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-(1H-Indol-5-Yl)Piperidine-1-Carboxylate
CAS No.	1049677-53-3
Molecular Formula	C18H24N2O2
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-4-(5-Indolyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1H-indol-5-yl)piperidine; 4-(1H-Indol-5-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(1H-indol-5-yl)-1-piperidinecarboxylate; 4-(1H-Indol-5-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(5-Indolyl)piperidine; 1049677-53-3; 5-(1-Boc-4-piperidyl)indole
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Indol-5-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.