Description

1-Boc-6-Amino-3,3-Dimethyl-2,3-Dihydro-Indole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive amino group protected by a tert-butoxycarbonyl (Boc) group, enabling precise and sequential chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Peptide Mimetics & Conjugates: Facilitates the creation of indole-based peptide analogs and bioconjugates for drug delivery and diagnostic applications.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Academic & Contract Research: Serves as a valuable reagent for methodological development and exploratory chemistry in R&D laboratories.

Basic Information

Product Name	1-Boc-6-Amino-3,3-Dimethyl-2,3-Dihydro-Indole
CAS No.	1049677-43-1
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	6-Amino-3,3-dimethyl-2,3-dihydro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 6-amino-3,3-dimethyl-2,3-dihydro-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-6-amino-3,3-dimethylindoline; 1-Boc-6-amino-3,3-dimethylindoline; Boc-6-Amino-DMI; 6-Amino-3,3-dimethylindoline-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Amino-3,3-Dimethyl-2,3-Dihydro-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.