Description

tert-Butyl4-Formylisoindoline-2-Carboxylate is a high-purity, versatile chemical building block essential for advanced organic synthesis. Its value lies in its dual functional groups, which make it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of isoindoline-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require the isoindoline scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in OLED displays and lighting due to its rigid, planar structure.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: The isoindoline core is utilized to create conformationally constrained peptide analogs for biochemical and medicinal chemistry studies.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with unique thermal or optical properties.

Basic Information

Product Name	tert-Butyl4-Formylisoindoline-2-Carboxylate
CAS No.	1049677-40-8
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	tert-Butyl 4-formyl-2,3-dihydro-1H-isoindole-2-carboxylate; 4-Formyl-1,3-dihydro-2H-isoindole-2-carboxylic acid tert-butyl ester; 2-(tert-Butoxycarbonyl)-1,3-dihydroisoindole-4-carboxaldehyde; Boc-4-formylisoindoline; tert-Butyl 4-formylisoindoline-2-carboxylate; 1,3-Dihydro-2H-isoindole-4-carboxaldehyde, 2-(1,1-dimethylethoxy)carbonyl]-; 2-Boc-4-formylisoindoline
EINECS	Contact for details

Quality Control

Our tert-Butyl4-Formylisoindoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.