Description

Imidazo[1,2-A]Pyridine, 8-Iodo-6-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and trifluoromethylated structure. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the biological activity of the imidazopyridine core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED emitters or charge-transport molecules.
• Chemical Biology Probes: Utilized in the design of fluorescent tags or molecular probes due to its modifiable halogen handle.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis for HTS: Employed in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine, 8-Iodo-6-(Trifluoromethyl)-
CAS No.	1048913-78-5
Molecular Formula	C8H4F3IN2
Molecular Weight	312.03 g/mol
Synonyms	8-Iodo-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 6-(Trifluoromethyl)-8-iodoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 8-iodo-6-(trifluoromethyl)-; 8-Iodo-6-trifluoromethylimidazo[1,2-a]pyridine; 1048913-78-5; AI3-63587; AKOS040750623; ZINC000257409810
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine, 8-Iodo-6-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support custom synthesis and can tailor purity grades (from >95% to >98%) to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.