Description

1-Bromo-3-(tert-Butyl)-5-Methoxybenzene is a high-purity, synthetically valuable halogenated aromatic building block. This compound matters as a versatile intermediate for constructing complex molecular architectures in advanced organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as ligand synthesis and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for creating complex aromatic cores.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its substituted benzene structure.
• Material Science & Organic Electronics: Serves as a precursor for synthesizing specialized ligands, monomers, and organic semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations due to the reactive bromine substituent.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the exploration of new synthetic pathways.
• Ligand & Catalyst Preparation: Useful for constructing sophisticated phosphine or nitrogen-based ligands used in homogeneous catalysis.

Basic Information

Product Name	1-Bromo-3-(tert-Butyl)-5-Methoxybenzene
CAS No.	1047661-27-7
Molecular Formula	C11H15BrO
Molecular Weight	243.14 g/mol
Synonyms	3-tert-Butyl-5-bromoanisole; 5-Bromo-3-tert-butylanisole; 1-Bromo-3-tert-butyl-5-methoxybenzene; 3-(tert-Butyl)-5-bromoanisole; Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-methoxy-; 5-Bromo-3-(1,1-dimethylethyl)anisole; 3-tert-Butyl-5-methoxybromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(tert-Butyl)-5-Methoxybenzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.