Description

2-Thiophenecarboxylic Acid, 4-Bromo-5-Methoxy-, Methyl Ester is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific bromo- and methoxy-substituted thiophene scaffold enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its bioactive thiophene core.
• Material Science Research: Serves as a precursor for functionalized monomers or ligands in the development of advanced polymers, conductive materials, or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes and target engagement.
• Organic Electronic Materials: Potential use in the synthesis of components for organic light-emitting diodes (OLEDs) or organic photovoltaics due to the electron-rich thiophene unit.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Item	Detail
Product Name	2-Thiophenecarboxylic Acid, 4-Bromo-5-Methoxy-, Methyl Ester
CAS No.	1047630-22-7
Molecular Formula	C8H7BrO3S
Molecular Weight	263.11 g/mol
Synonyms	Methyl 4-Bromo-5-methoxy-2-thiophenecarboxylate; 4-Bromo-5-methoxy-2-thiophenecarboxylic acid methyl ester; Methyl 4-bromo-5-methoxythiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 4-bromo-5-methoxy-, methyl ester; 4-Bromo-5-methoxy-thiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylic Acid, 4-Bromo-5-Methoxy-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.