Description

3-Amino-1-[3,4-Dihydro-2(1H)-Isoquinolinyl]-1-Propanone Hydrochloride is a high-purity organic salt compound with the CAS number 1046757-39-4. This specialized chemical serves as a critical building block in advanced pharmaceutical synthesis and fine chemical research. It is primarily required by R&D chemists and process development scientists working in medicinal chemistry and active pharmaceutical ingredient (API) manufacturing. The compound's unique structure makes it valuable for constructing complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step production of complex organic molecules for agrochemicals and specialty materials.
• Academic & Institutional R&D: Serves as a reagent for methodological development and the study of new organic reactions in university and government laboratories.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	3-Amino-1-[3,4-Dihydro-2(1H)-Isoquinolinyl]-1-Propanone Hydrochloride
CAS No.	1046757-39-4
Molecular Formula	C₁₂H₁₇ClN₂O
Molecular Weight	240.73 g/mol
Synonyms	1-(3,4-Dihydro-2(1H)-isoquinolinyl)-3-aminopropan-1-one hydrochloride; 3-Amino-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one hydrochloride; 1-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-3-aminopropan-1-one HCl; 3-Amino-1-(3,4-dihydro-1H-isoquinolin-2-yl)propan-1-one hydrochloride; 2-(3-Aminopropanoyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-1-[3,4-Dihydro-2(1H)-Isoquinolinyl]-1-Propanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.