Description

1,2,3,4-Tetrahydro-Isoquinoline-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused ring system and functional groups, making it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Organic Synthesis Building Block: Used in the construction of complex isoquinoline and tetrahydroisoquinoline derivatives for medicinal chemistry and material science.
• Agrochemical Research: Serves as a precursor in the synthesis of novel compounds for crop protection and agrochemical studies.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1,2,3,4-Tetrahydro-Isoquinoline-5-Carboxylic Acid
CAS No.	1044764-16-0
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	5-Carboxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-5-carboxylic acid; THIQ-5-COOH; 1,2,3,4-Tetrahydro-5-isoquinolinecarboxylic acid; 5-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-; 1044764-16-0; Tetrahydroisoquinoline-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Isoquinoline-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.