Description

p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]Phosphonic Acid Diethyl Ester is a high-value, multifunctional organophosphorus building block designed for advanced synthetic chemistry. This compound matters for its unique molecular architecture, which incorporates a bromo-cyano-naphthalene core linked to a difluoromethylphosphonate ester, enabling precise structural modifications in complex molecule assembly. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers with specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized to construct activity-based probes for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated phosphonate-based ligands for asymmetric catalysis.
• Organic Light-Emitting Diode (OLED) Materials: A key intermediate for synthesizing electron-transport or host materials in OLED devices.

Basic Information

Product Name	p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]Phosphonic Acid Diethyl Ester
CAS No.	1042170-70-6
Molecular Formula	C₁₇H₁₅BrF₂NO₃P
Molecular Weight	430.18 g/mol
Synonyms	Diethyl [(3-Bromo-6-cyano-2-naphthyl)difluoromethyl]phosphonate; Diethyl P-[(3-Bromo-6-cyano-2-naphthalenyl)difluoromethyl]phosphonate; Phosphonic acid, P-[(3-bromo-6-cyano-2-naphthalenyl)difluoromethyl]-, diethyl ester; 1042170-70-6; (3-Bromo-6-cyano-naphthalen-2-yl)-difluoromethyl-phosphonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our production of p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]Phosphonic Acid Diethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical research and development. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and LC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.