Description

p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]-Phosphonic Acid is a high-purity, advanced organic intermediate characterized by its unique naphthalene-based structure incorporating bromo, cyano, difluoromethyl, and phosphonic acid functional groups. This compound is critical for research and development in advanced material science and pharmaceutical chemistry, where precise molecular architecture is required. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries for constructing complex molecules and novel ligands.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Ligand Synthesis: Acts as a precursor for sophisticated phosphonate-based ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the creation of specialty polymers and advanced organic electronic materials requiring specific halogenated and phosphonated components.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme mechanisms and cellular pathways.
• Custom Synthesis & Scale-Up: A vital starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]-Phosphonic Acid
CAS No.	1042170-36-4
Molecular Formula	C₁₃H₇BrF₂NO₃P
Molecular Weight	374.08 g/mol
Synonyms	[4-[(3-Bromo-6-cyano-2-naphthyl)difluoromethyl]phosphonic acid]; 4-[(3-Bromo-6-cyanonaphthalen-2-yl)difluoromethyl]phosphonic acid; (3-Bromo-6-cyano-2-naphthalenyl)difluoromethylphosphonic acid; p-(3-Bromo-6-cyano-2-naphthyl)difluoromethylphosphonic acid; 1042170-36-4; Phosphonic acid, P-[3-bromo-6-cyano-2-naphthalenyl)difluoromethyl]-
EINECS	Contact for details

Quality Control

Every batch of p-[(3-Bromo-6-Cyano-2-Naphthalenyl)Difluoromethyl]-Phosphonic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.