Description

3-Chloro-6-Fluoro-Isoquinoline is a high-purity, halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which serves as a privileged structure for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the isoquinoline core.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The nitrogen and halogen atoms make it a candidate for designing novel ligands in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Chloro-6-Fluoro-Isoquinoline
CAS No.	1041423-28-2
Molecular Formula	C9H5ClFN
Molecular Weight	181.60 g/mol
Synonyms	3-Chloro-6-fluoro-isoquinoline; 6-Fluoro-3-chloroisoquinoline; Isoquinoline, 3-chloro-6-fluoro-; 1041423-28-2; 3-Chloro-6-fluoro-2-azanaphthalene
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-6-Fluoro-Isoquinoline is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.