Description

2-Propynoic Acid, 3-(3-Thienyl)- is a specialized organic building block featuring a propiolic acid core functionalized with a thiophene heterocycle. This unique structure makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where the thiophene moiety is a key pharmacophore. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that incorporate heterocyclic components for enhanced activity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of conductive polymers and specialty polymers with tailored electronic properties.
• Organic Electronics: Building block for organic semiconductors, OLED materials, and other electronic components due to the electron-rich thiophene unit.
• Chemical Research: A versatile reagent for click chemistry, Sonogashira coupling, and other metal-catalyzed cross-coupling reactions in academic and industrial R&D.
• Ligand Synthesis: Precursor for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Propynoic Acid, 3-(3-Thienyl)-
CAS No.	1041178-28-2
Molecular Formula	C7H4O2S
Molecular Weight	152.17 g/mol
Synonyms	3-(Thiophen-3-yl)propiolic acid; 3-(3-Thienyl)-2-propynoic acid; 3-Thiophen-3-ylpropynoic acid; Thiophene-3-propiolic acid; 3-(3-Thienyl)propiolic acid; 3-Thienylpropiolic acid; 3-(Thiophen-3-yl)prop-2-ynoic acid
EINECS	Contact for details

Quality Control

Our 2-Propynoic Acid, 3-(3-Thienyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is a strong acid/organic solvent and should be handled with appropriate personal protective equipment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.