Description

3,4-Dihydro-Pyrrolo[3,4-B]Indol-1(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused indole alkaloid class. This compound is of significant commercial interest as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating novel therapeutic agents targeting central nervous system disorders and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those with indole-based scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Employed in the process research and scale-up development of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Biochemical Tool Compound: Acts as a core structure for developing probes and inhibitors to study specific biological pathways and enzyme functions.
• Organic Synthesis: Utilized in academic and industrial laboratories for methodological development and the synthesis of complex natural product analogs.

Basic Information

Product Name	3,4-Dihydro-Pyrrolo[3,4-B]Indol-1(2H)-One
CAS No.	1040375-79-8
Molecular Formula	C10H8N2O
Molecular Weight	172.18 g/mol
Synonyms	1,2,3,4-Tetrahydropyrrolo[3,4-b]indol-1-one; 2,3-Dihydro-1H-pyrrolo[3,4-b]indol-1-one; Pyrrolo[3,4-b]indol-1(2H)-one, 3,4-dihydro-; 1040375-79-8; AI3-53131; SCHEMBL218062; ZINC000253899716; AKOS040759623
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-Pyrrolo[3,4-B]Indol-1(2H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.