Description

1-[(4R)-4-Phenyl-2-Thioxo-3-Thiazolidinyl]-1-Propanone is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its specific stereochemistry and functional groups, which are critical for synthesizing bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex heterocyclic compounds with a thioxothiazolidine core.
• Chemical Research & Development: Serves as a standard or reagent in method development and structure-activity relationship (SAR) studies within academic and industrial R&D labs.
• Precursor for Specialty Chemicals: Potential use in the synthesis of ligands for catalysis or advanced materials with specific optical properties.

Basic Information

Product Name	1-[(4R)-4-Phenyl-2-Thioxo-3-Thiazolidinyl]-1-Propanone
CAS No.	1039757-81-7
Molecular Formula	C12H11NOS2
Molecular Weight	249.35 g/mol
Synonyms	(4R)-4-Phenyl-3-(1-oxopropyl)-2-thioxo-1,3-thiazolidine; 1-Propanone, 1-[(4R)-4-phenyl-2-thioxo-3-thiazolidinyl]-; (R)-4-Phenyl-3-propionyl-2-thioxothiazolidine; 1-[(4R)-4-Phenyl-2-thioxo-1,3-thiazolidin-3-yl]propan-1-one; 3-Propionyl-4-phenyl-2-thioxo-1,3-thiazolidine (R-enantiomer)
EINECS	Contact for details

Quality Control

Our 1-[(4R)-4-Phenyl-2-Thioxo-3-Thiazolidinyl]-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.