Description

4-Iodotoluene-D7 is a deuterium-labeled isotopologue of 4-iodotoluene, a valuable building block in synthetic organic chemistry. This high-purity, isotopically enriched compound is essential for applications requiring precise molecular tracking and analysis, such as in mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing deuterated active pharmaceutical ingredients (APIs), conducting metabolic studies, and synthesizing labeled standards.

Application

• Deuterated Pharmaceutical Intermediate: A critical precursor for synthesizing deuterium-labeled drug candidates and active pharmaceutical ingredients (APIs) in drug discovery and development.
• Internal Standard for Mass Spectrometry: Used as a quantitative internal standard in LC-MS and GC-MS analysis for accurate measurement of 4-iodotoluene and related compounds in complex matrices.
• NMR Spectroscopy Solvent & Reagent: Employed as a probe or reagent in nuclear magnetic resonance (NMR) studies to investigate molecular structure, dynamics, and reaction mechanisms.
• Metabolic Pathway Tracing: Facilitates the study of metabolic pathways and pharmacokinetics (ADME) in biomedical research due to its isotopic label.
• Organic Synthesis Building Block: Serves as a versatile aryl iodide component in cross-coupling reactions (e.g., Suzuki, Stille) for creating complex, labeled organic molecules.
• Material Science Research: Used in the development of novel deuterated polymers, liquid crystals, and other advanced materials where isotopic substitution modifies physical properties.

Basic Information

Product Name	4-Iodotoluene-D7
CAS No.	1039678-66-4
Molecular Formula	C7D7I
Molecular Weight	221.05 g/mol
Synonyms	1-Iodo-4-(methyl-d3)benzene-2,3,5,6-d4; p-Iodotoluene-D7; 4-Methyl-d3-iodobenzene-2,3,5,6-d4; Deutero-p-iodotoluene; (2,3,5,6-Tetradeutero-4-trideuteromethyl)iodobenzene; Iodobenzene-d7, 4-methyl-; Perdeuterated 4-Iodotoluene
EINECS	Contact for details

Quality Control

Our 4-Iodotoluene-D7 is manufactured under strict quality control protocols to ensure high isotopic and chemical purity, essential for sensitive analytical and synthetic applications. Each batch is characterized by advanced analytical techniques including NMR, GC-MS, and HPLC to confirm deuterium incorporation and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (D-enrichment), chemical purity, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR / NMR)	Conforms to structure
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (GC)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.