Description

1H-Indole, 1-[(2-Bromophenyl)Sulfonyl]-4-[(4-Methyl-1-Piperazinyl)Methyl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. This compound is of significant commercial interest due to its unique indole core functionalized with both a bromophenylsulfonyl group and a methylpiperazinylmethyl moiety, offering versatile reactivity for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design and synthesis of potential kinase inhibitors.
• Chemical Biology Probes: Utilized in the creation of chemical probes to study specific biological targets and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	1H-Indole, 1-[(2-Bromophenyl)Sulfonyl]-4-[(4-Methyl-1-Piperazinyl)Methyl]-
CAS No.	1038988-11-2
Molecular Formula	C20H22BrN3O2S
Molecular Weight	448.38 g/mol
Synonyms	1-[(2-Bromophenyl)sulfonyl]-4-[(4-methylpiperazin-1-yl)methyl]-1H-indole; 4-[(4-Methylpiperazin-1-yl)methyl]-1-[(2-bromophenyl)sulfonyl]-1H-indole; 1-(2-Bromobenzenesulfonyl)-4-[(4-methylpiperazin-1-yl)methyl]indole; 1038988-11-2; Bromophenylsulfonyl indole piperazine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are provided with every shipment. We adhere to cGMP (current Good Manufacturing Practice) principles for the production of pharmaceutical intermediates, ensuring traceability and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.