Description

tert-Butyl (3S)-3-{4-[7-(Aminocarbonyl)-2H-Indazol-2-Yl]Phenyl}Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, offering researchers a precise and reliable chemical entity for drug discovery and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on creating innovative small-molecule drugs, particularly in oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a potential component in the design of bifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Synthesis: Employed in the construction of complex molecules designed to modulate kinase activity for therapeutic purposes.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	tert-Butyl (3S)-3-{4-[7-(Aminocarbonyl)-2H-Indazol-2-Yl]Phenyl}Piperidine-1-Carboxylate
CAS No.	1038916-11-8
Molecular Formula	C24H28N4O3
Molecular Weight	420.51 g/mol
Synonyms	1-Boc-3(S)-[4-(7-carbamoyl-2H-indazol-2-yl)phenyl]piperidine; (3S)-1-(tert-Butoxycarbonyl)-3-[4-(7-carbamoyl-1H-indazol-2-yl)phenyl]piperidine; tert-Butyl (3S)-3-[4-(7-carbamoyl-1H-indazol-2-yl)phenyl]piperidine-1-carboxylate; 1038916-11-8; BOC-Protected Indazole-Piperidine Carboxamide; 2-[4-[(3S)-1-(tert-Butoxycarbonyl)-3-piperidyl]phenyl]-1H-indazole-7-carboxamide
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S)-3-{4-[7-(Aminocarbonyl)-2H-Indazol-2-Yl]Phenyl}Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with the standards required for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.