Description

5-Hydroxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a versatile and high-value boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or phenolic motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalizing agent in the production of organic electronic materials, including OLEDs and conductive polymers.
• Chemical Research: An indispensable reagent in academic and industrial R&D for palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel bidentate ligands and organometallic catalysts.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance, dye, and specialty chemical compounds.

Basic Information

Product Name	5-Hydroxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1038827-60-9
Molecular Formula	C₁₃H₁₇BO₄
Molecular Weight	248.09 g/mol
Synonyms	5-Formyl-2-hydroxyphenylboronic acid pinacol ester; 2-Formyl-4-hydroxyphenylboronic acid pinacol ester; 5-Hydroxy-2-formylphenylboronic acid pinacol ester; 2-(5-Formyl-2-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Hydroxy-2-(pinacolatoboryl)benzaldehyde; 5-Hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 5-Hydroxy-2-(pinacolboron)benzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.