Description

Methyl 3-Amino-5-Bromobenzo[B]Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzothiophene core structure. This compound is essential for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create complex molecules with potential biological activity. The product is supplied with full analytical documentation to ensure reliability and reproducibility in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) in drug discovery.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides.
• Material Science: A potential monomer or precursor for creating organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic and organic chemistry.

Basic Information

Product Name	Methyl 3-Amino-5-Bromobenzo[B]Thiophene-2-Carboxylate
CAS No.	1036380-75-2
Molecular Formula	C10H8BrNO2S
Molecular Weight	286.15 g/mol
Synonyms	Methyl 3-amino-5-bromobenzo[b]thiophene-2-carboxylate; 5-Bromo-3-aminobenzo[b]thiophene-2-carboxylic acid methyl ester; 3-Amino-5-bromobenzo[b]thiophene-2-carboxylic acid methyl ester; Methyl 5-bromo-3-aminobenzo[b]thiophene-2-carboxylate; 2-Carbomethoxy-3-amino-5-bromobenzo[b]thiophene; 1036380-75-2; Methyl 3-Amino-5-Bromobenzo[B]Thiophene-2-Carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Bromobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with relevant guidelines for advanced intermediates in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.