Description

2-Methyl-4-(Trifluoromethyl)-1,3-thiazole-5-carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole ring substituted with a trifluoromethyl group and an aldehyde functionality. This compound is of significant commercial importance due to its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought after by research institutions, agrochemical developers, and pharmaceutical companies engaged in the discovery and production of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules for drug discovery, especially for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl-thiazole moiety contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a building block for creating novel organic ligands, catalysts, and functional materials with specific electronic or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways due to its reactive aldehyde group.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethyl)-1,3-thiazole-5-carbaldehyde
CAS No.	1034566-13-6
Molecular Formula	C6H4F3NOS
Molecular Weight	195.16 g/mol
Synonyms	5-Formyl-2-methyl-4-(trifluoromethyl)thiazole; 2-Methyl-4-trifluoromethyl-1,3-thiazole-5-carboxaldehyde; 4-(Trifluoromethyl)-2-methyl-1,3-thiazole-5-carbaldehyde; 2-Methyl-4-(trifluoromethyl)thiazole-5-carbaldehyde; 5-Aldehyde-2-methyl-4-trifluoromethylthiazole; MFCD28425322
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Trifluoromethyl)-1,3-thiazole-5-carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.