Description

Benzo[B]Thiophene-2-Methanol, α-(5-Bromo-2-Fluorophenyl)- is a high-value, multi-functional organic building block characterized by its unique heterocyclic thiophene core substituted with bromo and fluoro aromatic groups. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, offering chemists precise control over molecular architecture for advanced material and pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate halogenated benzothiophene motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in developing new generation herbicides and fungicides, where the halogenated benzothiophene structure can contribute to biological activity and environmental stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of organic semiconductors, conductive polymers, and liquid crystals for electronic applications.
• Chemical Synthesis: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its reactive alcohol and halogen functional groups.
• Fluorescent Probe Development: Utilized in the design and synthesis of fluorescent dyes and molecular probes for bioimaging and diagnostic assays.

Basic Information

Product Name	Benzo[B]Thiophene-2-Methanol, α-(5-Bromo-2-Fluorophenyl)-
CAS No.	1034305-11-7
Molecular Formula	C15H10BrFOS
Molecular Weight	337.21 g/mol
Synonyms	α-(5-Bromo-2-fluorophenyl)-1-benzothiophene-2-methanol; (5-Bromo-2-fluorophenyl)(1-benzothiophen-2-yl)methanol; 2-[(5-Bromo-2-fluorophenyl)(hydroxy)methyl]benzo[b]thiophene; 1-Benzothiophene-2-methanol, α-(5-bromo-2-fluorophenyl)-; Benzo[b]thiophen-2-yl(5-bromo-2-fluorophenyl)methanol
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Methanol, α-(5-Bromo-2-Fluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its chemical properties, keep away from strong bases and fluorides. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.