Description

5-Formyl-1H-Indazole-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized indazole derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the dual reactive sites—the formyl and ester groups—which enable precise, multi-step derivatization for constructing complex heterocyclic scaffolds. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients targeting a range of therapeutic areas and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science Precursor: Employed in the research of organic electronic materials and advanced polymers due to its conjugated indazole core.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	5-Formyl-1H-Indazole-3-Carboxylic Acid Methyl Ester
CAS No.	1033772-29-0
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 5-formyl-1H-indazole-3-carboxylate; 1H-Indazole-3-carboxylic acid, 5-formyl-, methyl ester; 5-Formylindazole-3-carboxylic acid methyl ester; 3-Methoxycarbonyl-1H-indazole-5-carboxaldehyde; 5-Formyl-1H-indazole-3-carboxylic acid methyl ester; Methyl 5-formylindazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Formyl-1H-Indazole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.