Description

(S)-1-(tert-Butoxycarbonyl)-5-Oxopiperazine-2-Carboxylic Acid is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is essential for the efficient and stereoselective construction of complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide mimetics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, including protease inhibitors and other biologically active molecules.
• Peptidomimetic Synthesis: Used to incorporate constrained, non-proteinogenic amino acid structures into peptides to enhance stability, bioavailability, and binding affinity.
• API Process Development: Serves as a building block in the scalable synthesis of Active Pharmaceutical Ingredients (APIs) under current Good Manufacturing Practice (cGMP) guidelines.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and inhibitors for studying enzyme function and protein-protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereocontrolled reactions to introduce specific three-dimensional configurations into target molecules.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical market.

Basic Information

Item	Details
Product Name	(S)-1-(tert-Butoxycarbonyl)-5-Oxopiperazine-2-Carboxylic Acid
CAS No.	1033713-11-9
Molecular Formula	C10H16N2O5
Molecular Weight	244.25 g/mol
Synonyms	(2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-5-oxopiperazine-2-carboxylic acid; (S)-1-Boc-5-oxopiperazine-2-carboxylic acid; (S)-1-(Boc)-5-oxopiperazine-2-carboxylic acid; (S)-5-Oxo-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid; (S)-1-N-Boc-5-oxopiperazine-2-carboxylic acid; Boc-(S)-5-oxopiperazine-2-COOH; (S)-1-tert-Butoxycarbonyl-5-oxopiperazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-1-(tert-Butoxycarbonyl)-5-Oxopiperazine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to meet the exacting standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.