Description

5-Nitro-1,3-Dihydro-2H-Indol-2-One is a specialized nitro-substituted indolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for researchers and manufacturers in the life sciences sector who require high-purity building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its nitro-aromatic functionality.
• Material Science Precursor: Serves as a monomer or precursor in the synthesis of advanced organic materials and functional dyes.
• Academic & R&D Laboratories: Employed in methodological studies and as a reference standard in analytical chemistry for method development.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions and other modern synthetic transformations to introduce the indolinone core.

Basic Information

Product Name	5-Nitro-1,3-Dihydro-2H-Indol-2-One
CAS No.	1032268-18-0
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	5-Nitroindolin-2-one; 2H-Indol-2-one, 1,3-dihydro-5-nitro-; 5-Nitro-2-indolinone; 5-Nitro-2-oxindole; 5-Nitroindole-2-one; 5-Nitro-2,3-dihydro-1H-indol-2-one
EINECS	Contact for details

Quality Control

Our 5-Nitro-1,3-Dihydro-2H-Indol-2-One is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, prolonged exposure to light and air should be avoided. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.