Description

D3-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-[2-(1-Methyl-Pyrrolidin-2-Yl)-Ethyl]-4-Propoxy-Benzenesulfonamide is a high-purity, non-peptidic small molecule compound of significant interest in pharmaceutical research and development. This compound matters as a key chemical entity for investigating novel therapeutic pathways, particularly in the areas of urology and cardiovascular medicine. It is primarily needed by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery and preclinical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard and a probe compound in biochemical assays and target validation studies.
• Drug Discovery Programs: Employed in high-throughput screening (HTS) and structure-activity relationship (SAR) studies for novel drug candidates.
• Preclinical Development: Utilized in pharmacokinetic, pharmacodynamic, and toxicology studies during the early stages of drug development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing specialized research and custom synthesis services.
• Academic Research: Used in university laboratories for fundamental research in medicinal chemistry and pharmacology.

Basic Information

Product Name	D3-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-[2-(1-Methyl-Pyrrolidin-2-Yl)-Ethyl]-4-Propoxy-Benzenesulfonamide
CAS No.	1032008-25-5
Molecular Formula	C26H38N6O4S
Molecular Weight	530.69 g/mol
Synonyms	D3-3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzenesulfonamide; Avanafil Impurity; Avanafil Related Compound D3; Tadalafil Analog; PDE5 Inhibitor Intermediate; Sulfonamide Pyrazolopyrimidinone Derivative; 4-Propoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzenesulfonamide Derivative
EINECS	Contact for details

Quality Control

Our D3-3-(1-Methyl-7-Oxo-3-Propyl-6,7-Dihydro-1H-Pyrazolo[4,3-D]Pyrimidin-5-Yl)-n-[2-(1-Methyl-Pyrrolidin-2-Yl)-Ethyl]-4-Propoxy-Benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.