Description

2-(5-Bromo-2-Methylbenzyl)-5-(4-Fluorophenyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated thiophene structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Employed in complex organic reactions, including cross-coupling and functional group transformations, due to its reactive bromine and thiophene moieties.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or precursor for functional organic materials, such as organic semiconductors or conductive polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-(5-Bromo-2-Methylbenzyl)-5-(4-Fluorophenyl)Thiophene
CAS No.	1030825-20-7
Molecular Formula	C18H14BrFS
Molecular Weight	361.27 g/mol
Synonyms	5-(4-Fluorophenyl)-2-[(5-bromo-2-methylphenyl)methyl]thiophene; 2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene; 1030825-20-7; 5-(4-Fluorophenyl)-2-((5-bromo-2-methylbenzyl)thiophene; Thiophene, 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Bromo-2-Methylbenzyl)-5-(4-Fluorophenyl)Thiophene is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our quality commitment includes providing a detailed Certificate of Analysis (COA) with each shipment, which reports key parameters such as assay purity and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.