Description

8-Bromo-3-chloroisoquinoline is a high-purity halogenated isoquinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique bifunctional halogenated structure, which enables selective cross-coupling reactions and the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides due to its bioactive heterocyclic core.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysis, and specialty polymers.
• Cross-Coupling Reactions: The bromo and chloro substituents allow for sequential, site-selective metal-catalyzed couplings (e.g., Suzuki, Buchwald-Hartwig, Negishi).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry and heterocyclic compound exploration.

Basic Information

Product Name	8-Bromo-3-chloroisoquinoline
CAS No.	1029720-63-5
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	3-Chloro-8-bromoisoquinoline; 8-Bromo-3-chloro-isoquinoline; Isoquinoline, 8-bromo-3-chloro-; 1029720-63-5
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-chloroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.