Description

6-Hydroxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity organic building block and synthetic intermediate of significant commercial interest. Its core value lies in its functionalized benzothiophene scaffold, which is a privileged structure in medicinal chemistry and advanced material science. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting a range of therapeutic areas, leveraging the benzothiophene core's bioactivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the thiophene moiety can impart specific biological activity.
• Material Science Precursor: Serves as a monomer or functional unit in the research of organic semiconductors, conductive polymers, and non-linear optical materials.
• Chemical Synthesis: Versatile intermediate for further functionalization, including hydrolysis to the corresponding acid, or use in cross-coupling reactions to create complex molecular architectures.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies and the discovery of new chemical entities.

Basic Information

Item	Details
Product Name	6-Hydroxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	1029720-28-2
Molecular Formula	C10H8O3S
Molecular Weight	208.23 g/mol
Synonyms	Methyl 6-Hydroxybenzo[b]thiophene-2-carboxylate; 6-Hydroxy-1-benzothiophene-2-carboxylic acid methyl ester; 2-(Methoxycarbonyl)-6-hydroxybenzo[b]thiophene; 6-Hydroxybenzo[b]thiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our production of 6-Hydroxy-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consideration should be given to maintaining an inert atmosphere (e.g., under nitrogen or argon). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.