Description

tert-Butyl 7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile and protected indole scaffold for further functionalization. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its functionalized tetrahydrocyclopentaindole core.
• API Development: Serves as a precursor in multi-step synthetic routes for the production of investigational new drugs (INDs).
• Process Chemistry: Employed in scale-up and route scouting for efficient and cost-effective manufacturing of target molecules.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological systems and target validation.

Basic Information

Item	Details
Product Name	tert-Butyl 7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Ylcarbamate
CAS No.	1029691-17-5
Molecular Formula	C₁₇H₁₉N₃O₂
Molecular Weight	297.35 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-7-cyano-1,2,3,4-tetrahydrocyclopenta[b]indole; 7-Cyano-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl-carbamic acid tert-butyl ester; tert-Butyl N-(7-cyano-1,2,3,4-tetrahydrocyclopenta[b]indol-2-yl)carbamate; 7-Cyano-2-N-Boc-1,2,3,4-tetrahydrocyclopenta[b]indole; 2-N-Boc-7-cyano-THCPI; Boc-7-cyano-THCPI; 1029691-17-5
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 7-Cyano-1,2,3,4-Tetrahydrocyclopenta[B]Indol-2-Ylcarbamate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical pharmaceutical applications. All materials undergo comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting full specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.