Description

8-Methoxycarbonyl-1,2,3,4-Tetrahydroisoquinoline Hcl is a high-purity, functionalized tetrahydroisoquinoline derivative, a versatile and critical building block in advanced organic synthesis. Its value lies in its role as a key chiral intermediate for constructing complex pharmacologically active molecules, enabling the development of new therapeutic agents. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on central nervous system (CNS) drugs, alkaloid synthesis, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates targeting neurological disorders, such as Parkinson's disease and depression.
• Alkaloid Synthesis: Serves as a core scaffold for the construction of complex natural product analogs and isoquinoline-based alkaloids.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor binding.
• Asymmetric Catalysis Substrate: Acts as a substrate for testing and developing new chiral catalysts and synthetic methodologies.
• Custom Synthesis Building Block: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Item	Details
Product Name	8-Methoxycarbonyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	1029689-82-4
Molecular Formula	C12H15NO2 • HCl
Molecular Weight	241.71 g/mol
Synonyms	8-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride; Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate hydrochloride; 1,2,3,4-Tetrahydro-8-isoquinolinecarboxylic acid methyl ester hydrochloride; 8-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline HCl; THIQ-8-COOMe HCl; 8-Methoxycarbonyl-THIQ HCl
EINECS	Contact for details

Quality Control

Our 8-Methoxycarbonyl-1,2,3,4-Tetrahydroisoquinoline Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.