Description

Diethyl 2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate (API intermediate) characterized by its unique fused cyclopentathiophene core. This compound is a critical building block in modern organic synthesis, enabling the construction of complex heterocyclic scaffolds with significant biological potential. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel active pharmaceutical ingredients (APIs) with potential activity in central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new generation herbicides and pesticides, leveraging its heterocyclic structure for targeted biological activity.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing organic semiconductors and conductive polymers due to the electron-rich thiophene moiety.
• Dye and Pigment Synthesis: Intermediate for creating specialized organic dyes and pigments where the aminothiophene structure imparts specific color and stability properties.
• Academic and R&D: Essential for methodological development in organic chemistry, particularly in studies involving cyclopenta-fused heterocycles and multicomponent reactions.

Basic Information

Item	Details
Product Name	Diethyl 2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate
CAS No.	1029689-54-0
Molecular Formula	C13H17NO4S
Molecular Weight	283.34 g/mol
Synonyms	2-Amino-4,5-dihydro-6H-cyclopenta[b]thiophene-3,4-dicarboxylic acid diethyl ester; Diethyl 2-amino-4,5-dihydro-6H-cyclopenta[b]thiophene-3,4-dicarboxylate; 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylic Acid Diethyl Ester; Ethyl 2-amino-4,5-dihydro-6H-cyclopenta[b]thiophene-3,4-dicarboxylate; CAS 1029689-54-0; Cyclopentathiophene dicarboxylate ester intermediate
EINECS	Contact for details

Quality Control

Our production of Diethyl 2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3,4-Dicarboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting applications in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.