Description

2-Methoxy-6-Phenylpyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, especially those containing complex pyridine and biphenyl scaffolds for oncology, CNS, and anti-inflammatory applications.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a highly effective boronic acid coupling partner for forming carbon-carbon bonds with aryl/heteroaryl halides, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific aryl-pyridine motifs for bioactivity.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Synthesis: Utilized for creating molecular probes and bioconjugates for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales, from research to pilot plant.

Basic Information

Product Name	2-Methoxy-6-Phenylpyridine-3-Boronic Acid
CAS No.	1029654-26-9
Molecular Formula	C12H12BNO3
Molecular Weight	229.04 g/mol
Synonyms	(6-Methoxy-2-phenylpyridin-3-yl)boronic acid; 2-Phenyl-6-methoxypyridine-3-boronic acid; 3-Borono-2-methoxy-6-phenylpyridine; 2-Methoxy-6-phenyl-3-pyridineboronic acid; 1029654-26-9; 6-Methoxy-2-phenyl-3-pyridineboronic acid; 2-Methoxy-6-phenylpyridin-3-ylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-Phenylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.