Description

6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid is a high-purity boronic acid derivative used as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The product is supplied with a CAS number of 1028745-48-3.

Application

This versatile boronic acid pinacol ester derivative serves as a critical building block in modern synthetic chemistry, with key applications including:

• Pharmaceutical Intermediates: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its pyridine and tetrahydropyran motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and functionalized polymers.
• Chemical Biology Probes: Serves as a precursor for creating tagged molecules used in proteomics and diagnostic assay development.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new chemical space in both university and corporate research laboratories.

Basic Information

Product Name	6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid
CAS No.	1028745-48-3
Molecular Formula	C10H14BNO3
Molecular Weight	207.04 g/mol
Synonyms	6-[(Oxan-4-yl)oxy]pyridine-3-boronic acid; (6-((Tetrahydro-2H-pyran-4-yl)oxy)pyridin-3-yl)boronic acid; 6-(Tetrahydropyran-4-yloxy)-3-pyridineboronic acid; 3-Borono-6-(tetrahydropyran-4-yloxy)pyridine; THP-Protected Pyridine Boronic Acid; 1028745-48-3; Pyridine-3-boronic acid, 6-(tetrahydro-2H-pyran-4-yloxy)-
EINECS	Contact for details

Quality Control

Our 6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.