Description

Methyl 1,2,3,4-Tetrahydroisoquinolin-8-Carboxylate is a high-purity heterocyclic building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in its versatile isoquinoline scaffold, which serves as a privileged structure for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create complex molecules with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing novel pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds, alkaloids, and natural product analogs in academic and industrial R&D.
• Material Science: Potential intermediate for synthesizing organic ligands, dyes, or functional polymers with specific electronic or photophysical properties.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and tool compounds for studying biological pathways and enzyme functions.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydroisoquinolin-8-Carboxylate
CAS No.	1028330-54-2
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	8-Methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; Methyl 8-isoquinolinecarboxylate, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydroisoquinoline-8-carboxylic acid methyl ester; 1,2,3,4-Tetrahydro-8-isoquinolinecarboxylic acid methyl ester; 8-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydroisoquinolin-8-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring suitability for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.